温州大学化学与材料工程学院

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科学研究

祝贺陈久喜和吴华悦老师指导研究生在ORGANIC & BIOMOLECULAR CHEMISTRY上发表学术论文

发布时间:2017-04-13 来源: 编辑: 点击[点击关闭]

标题:Copper-catalyzed C–O bond cleavage and cyclization: synthesis of indazolo[3,2-b]quinazolinones


Abstact
The first example of a copper-catalyzed halogen-free protocol to construct indazolo[3,2-b]quinazolinones was developed through sequential inert C–O bond cleavage followed by intramolecular C–N bond formation. This protocol represents an efficient synthetic tool for accessing a more diverse range of functionalized indazolo[3,2-b]quinazolinones. The structure of the newly synthesized indazolo[3,2-b]quinazolinones was unambiguously confirmed by X-ray crystal diffraction analysis.

链接:http://pubs.rsc.org/is/content/articlehtml/2017/ob/c6ob02352e
C6OB02352E