温州大学化学与材料工程学院

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高文霞

发布时间:2014-11-14 来源: 编辑: 点击[点击关闭]

个人简介

高文霞,女,副教授,毕业于合肥工业大学,主要从事微纳米药物载体的制备及其性能研究。
电子邮件:wenxiag@wzu.edu.cn
电话:13957778035
主要研究论文

1.        Yan Liang, Wenxia Gao,* Xinyu Peng, Xin Deng, Changzhen Sun, Huayue Wu, Bin He*. Near infrared light responsive hybrid nanoparticles for synergistic therapy. Biomaterials 2016, 100, 76-90.

2.     Yalong Hu, Wenxia Gao*, Fang Wu, Huayue Wu, Bin He, Jing He*. Low molecular weight gels induced differentiations of mesenchymal stem cells. J. Mater. Chem. B, 2016, 4, 3504-3508. .

3.    Long Xu, Yalong Hu, Miaochang Liu, Jiuxi Chen, Xiaobo Huang, Wenxia Gao*, Huayue Wu*. Gelation properties and glucose-sensitive behavior of phenylboronic acid based low-molecular-weight organogels. Tetrahedron, 2015, 71, 2079-2088..

4.    Kaiwen Yang, Sicheng Wan, Binbin Chen, Wenxia Gao*, Jiuxi Chen, Miaochang Liu, Huayue Wu*. Dual pH and temperature responsive hydrogels based β-cyclodextrin derivatives for atorvastatin delivery. Carbohy. Polym., 2015, 136, 300-306. .

5.    Chaoyu Zhou, Wenxia Gao*, Kaiwen Yang, Long Xu, Jiuxi Chen, Miaochang Liu, Xiaobo Huang, Huayue Wu*. A novel glucose/pH responsive low-molecular-weight organogel of easy recycling. Langmuir, 2013, 29, 13568-13575. .

6.   Chaoyu Zhou, Wenxia Gao*, Guangming Lu, Xiuming Wu, Xiaobo Huang, Jiuxi Chen, Huayue Wu*. Preparation, characterization and in vitro release of microparticles based on dextran-rosuvastatin conjugate. Carbohy. Polym., 2013, 96, 156-162.

7.    Xiepeng Lin, Wenxia Gao*, Chenen Li, Jiuxi Chen, Chen Yang, Huayue Wu*. Nano-sized flake carboxymethyl cassava starch as excipient for solid dispersions. Int. J. Pharmaceut., 2012, 423, 435-439.

8.    Wenxia Gao, Xiaoqing Lin, Xiepeng Lin, Jinchang Ding, Xiaobo Huang, Huayue Wu*. Preparation of nano-sized flake carboxymethyl cassava starch under ultrasonic irradiation. Carbohy. Polym., 2011, 84, 1413-1418.

9.    Xiepeng Lin, Wenxia Gao*, Xiaobo Huang, Panlong Zang, Jiuxi Chen, Huayue Wu*. Morphology-controlled hollow nanospheres of functionalized dextran by self-assembly in aqueous solution. Carbohy. Polym.,, 2010, 82, 460-465.

10.    Yanze Liu, Yunxiang Lei, Fei Li, Jiuxi Chen, Miaochang Liu, Xiaobo Huang*, Wenxia Gao, Huayue Wu*. Jinchang Ding, Yixiang Cheng*. Indene-1,3-dionemethylene-4H-pyran derivatives containing alkoxy chains of various lengths: aggregation-induced emission enhancement, mechanofluorochromic properties and solvent-induced emission changes, J. Mater. Chem. C 2016, DOI: 10.1039/C5TC02932E.

11.  Yunxiang Lei, Yanze Liu, Yang Guo, Jiuxi Chen, Xiaobo Huang*, Wenxia Gao, Lebin Qian, Huayue Wu*, Miaochang Liu, Yixiang Cheng*. Multi-Stimulus-Responsive Fluorescent Properties of Donor-π-Acceptor Indene-1,3-dionemethylene-1,4-dihydropyridine Derivatives, J. Phys. Chem. C 2015, 119, 23138-23148.

12.  Weiguang Yang, Rui Qiao, Jiuxi Chen*, Xiaobo Huang, Miaochang Liu, Wenxia Gao, Jinchang Ding, Huayue Wu*. Palladium-catalyzed cascade reaction of 2-amino-N-arylbenzohydrazides with triethyl orthobenzoates to construct indazolo[3,2-b]quinazolinones, J. Org. Chem. 2015, ASAP, DOI: 10.1021/jo5024848

13.   Yunxiang Lei, Hui Li, Xiaobo Huang*, Jiuxi Chen, Miaochang Liu, Wenxia Gao, Jinchang Ding, Dajie Lin, Huayue Wu*. Water-soluble benzoselenadiazole-based conjugated polymer fluorescent sensor with high selectivity for ferric ions and mercury ions and possible applications as integrated molecular logic gates, Tetrahedron, 2015, 71, 3453-3462.

14.   Hui Li, Yang Guo, Yunxiang Lei, Gao, Wenxia Gao, Miaochang Liu, Jiuxi Chen, Yuefei Hu, Xiaobo Huang*, Huayue Wu*. Dyes Pigm. 2015, 112, 105-115.

15.   Yunxiang Lei, Hui Li, Wenxia Gao, Miaochang Liu, Jiuxi Chen, Jinchang Ding, Xiaobo Huang*, Huayue Wu*. J. Mater. Chem. C 2014, 2, 7402-7410.

16.   Yan Shen, Jiuxi Chen*, Miaochang Liu, Jinchang Ding, Wenxia Gao, Xiaobo Huang, Huayue Wu*. Copper-catalyzed direct C-H arylation of pyridine N-oxides with arylboronic esters: one-pot synthesis of 2-arylpyridines, Chem. Commun. 2014, 50, 4292-4295.

17.   Zhongyan Chen, Jiuxi Chen*, Miaochang Liu, Jinchang Ding, Wenxia Gao, Xiaobo Huang, Huayue Wu*. Unexpected copper-catalyzed cascade synthesis of quinazoline derivatives, J. Org. Chem. 2013, 78, 11342-11348.

18.   Miaochang Liu, Shaomiao Lin, Jinchang Ding, Wenxia Gao, Huayue Wu, Jiuxi Chen*. Decarboxylation of isatoic anhydrides with disul?des: an effcient and general synthesis of S-aryl 2-aminobenzothioate derivatives, Tetrahedron 2013, 69, 2283-2288.

19.   Gaigai Liang, Miaochang Liu, Jiuxi Chen,* Jinchang Ding, Wenxia Gao and Huayue Wu*. NBS-promoted sulfenylation of sulfinates with disulfides leading to unsymmetrical or symmetrical thiosulfonates, Chin. J. Chem.2012, 30, 1611-1616.

20.   Wei Lu, Jiuxi Chen,* Miaochang Liu, Jinchang Ding, Wenxia Gao, Huayue Wu*, Palladium-catalyzed decarboxylative coupling of isatoic anhydrides with arylboronic acids, Org. Lett. 2011, 13, 6114-6117.

21.   Xingwang Zheng, Jinchang Ding, Jiuxi Chen*, Wenxiao Gao, Miaochang Liu, Huayue Wu*. The coupling of arylboronic acids with nitroarenes catalyzed by rhodium. Org. Lett., 2011, 13, 17261729.

22.   Yong Peng, Jiuxi Chen,* Jinchang Ding, Miaochang Liu, Wenxiao Gao, Huayue Wu*. Ligand-free copper-catalyzed arylation of olefins by the MizorokiHeck reaction. Synthesis 2011, 213-216.

23.   Tieqiang Huang, Jun Li, Jiuxi Chen,* Wenxia Gao, Jinchang Ding, Huayue Wu*. Silica sulfuric acid (SSA)/peg as a recyclable system for the synthesis of quinoxalines and pyrazines, Synth. Commun. 2011, 41, 3334-3343.

24.   Wenxue Guo, Guangshu Lv, Jiuxi Chen*, Wenxia Gao, Jinchang Ding, Huayue Wu*. Rongalite? and base-promoted cleavage of disulfides and subsequent Michael addition to α,β-unsaturated ketones/esters: an odorless synthesis of β-sulfido carbonyl compounds, Tetrahedron, 2010, 66, 22972300.

25.   Xiaoling Xu, Jiuxi Chen*, Wenxia Gao, Huayue Wu*, Jinchang Ding, Weike Su. Palladium-catalyzed hydroarylation of alkynes with arylboronic acids, Tetrahedron, 2010,66,24332438.

 

Yalong Hu, Wenxia Gao*, Fang Wu, Huayue Wu, Bin He, Jing He*. Low molecular weight gels induced differentiations of mesenchymal stem cells. J. Mater. Chem. B, 2016, DOI: 10.1039/C5TB02546J. (IF=4.726)
主要科研项目

1.  浙江省自然科学基金(主持):《基于有机小分子凝胶非共价方式“门控”的智能介孔骨架型药物载体的构建及性能研究》,2015-2017No.LY15B020001

2.  国家自然科学青年基金(主持):《葡萄糖快速响应型有机小分子凝胶的设计、合成及性能研究》,2013-2015No.21202122

3.  浙江省科技厅(主持):《有机硼酸小分子凝胶类胰岛素控释材料的设计合成与应用开发研究》,2013-2014No.2013C33188

4.  浙江省有机化学与皮革化工重中之重学科开放基金(主持):《智能型胰岛素口服凝胶的设计及合成》,2011-2012No.100061200109

5.  温州市科技局(主持):《5-氨基-2--N-(2,4-二甲苯基)-苯磺酰胺清洁生产工艺开发》,2009-2011G20090079

6.  国家自然科学青年基金(排名第二):《过渡金属催化靛红酸酐与有机硼酸的脱羧偶联反应研究》,2012-2014No.21102105

授权专利

1.      吴华悦,高文霞,刘妙昌,陈久喜,韩丹丹,狄安利,池艳艳,金杰,“一种杀扑磷纳米乳剂及其制备方法”,2014123日,中国,ZL201210376780.0  

2.      吴华悦,高文霞,陈久喜,刘妙昌,黄小波,池艳艳,金杰,“一种杀扑磷皮克林水乳剂及其制备方法”,2015422日,中国,ZL201310272281.1

3.      高文霞,吴华悦,李晨恩,刘妙昌,陈久喜,韩丹丹,狄安利,池艳艳,金杰,“一种氯氰菊酯水乳剂及其制备方法”, 2013731,中国,ZL201110331083.9

4.      高文霞,吴华悦,陈久喜,刘妙昌,林勰鹏,杨臣,“一种纳米级片状羧甲基淀粉钠在固体分散体中的应用”,201373,中国,ZL201110339510.8

5.      吴华悦,高文霞,刘妙昌,陈久喜,周超宇,卢广敏 ,“一种瑞舒伐他汀-右旋糖酐酯的制备方法”,201418,中国,ZL201110329343.9

6.      吴华悦,高文霞,陈久喜,刘妙昌,林勰鹏,“一种纳米级片状羧甲基淀粉钠的制备方法”, 2013116,中国,ZL201110009231.5

7.      高文霞,徐龙,吴华悦,陈久喜,刘妙昌,黄小波,蒋俊,一类苯硼酸类有机凝胶化合物,2013.12.25,浙江,CN201310361889.1

8.      高文霞,吴华悦,周超宇,陈久喜,刘妙昌,黄小波,蒋俊,万思成,一种苯硼酸类有机凝胶化合物,2013.5.1-2032.9.29,浙江,CN201210375089.0

主要获奖情况

·  2015,浙江省151人才第三层次

·  2014,温州市551人才第二层次

·  2012,温州市551人才第三层次   

·  2012,第十四届温州市自然科学优秀论文奖

·  2010,浙江省第六届青年教师教学技能奖